Product Description
| Purity |
|
99%+ |
Private customization |
2mg 5mg 10mg 15mg 20mg 30me etc. |
| Cleanliness |
|
Sterile |
Transportation time |
7-15days |
| Actual peptide content |
|
Exceed the standard |
Disguise |
Can provide |
| Test Report |
|
COA HPLC Third party testing |
Resend policy |
According to different countries |
| Customized top color |
|
Red Yellow Blue Black Purple White Green |
Payment method |
Bank Transfer BTC USDT Paypal |
Company Profile
Aging muscle experiences functional decline in part mediated by impaired mitochondrial ADP sensitivity. Elamipretide (ELAM) rapidly improves physiological and mitochondrial function in aging and binds directly to the mitochondrial ADP transporter ANT. We hypothesized that ELAM improves ADP sensitivity in aging leading to rescued physiological function. We measured the response to ADP stimulation in young and old muscle mitochondria with ELAM treatment, in vivo heart and muscle function, and compared protein abundance, phosphorylation, and S-glutathionylation of ADP/ATP pathway proteins. ELAM treatment increased ADP sensitivity in old muscle mitochondria by increasing uptake of ADP through the ANT and rescued muscle force and heart systolic function. Protein abundance in the ADP/ATP transport and synthesis pathway was unchanged, but ELAM treatment decreased protein s-glutathionylation incuding of ANT. Mitochondrial ADP sensitivity is rapidly modifiable. This research supports the hypothesis that ELAM improves ANT function in aging and links mitochondrial ADP sensitivity to physiological function. ELAM binds directly to ANT and ATP synthase and ELAM treatment improves ADP sensitivity, increases ATP production, and improves physiological function in old muscles. ADP (adenosine diphosphate), ATP (adenosine triphosphate), VDAC (voltage-dependent anion channel), ANT (adenine nucleotide translocator), H+ (proton), ROS (reactive oxygen species), NADH (nicotinamide adenine dinucleotide), FADH2 (flavin adenine dinucleotide), O2 (oxygen), ELAM (elamipretide), -SH (free thiol), -SSG (glutathionylated protein).
Cocer Pharmaceutical
Started in 1990, focusing on peptide products for 34 years
All products have passed the strict quality inspection of the Czech Janoshik institution to reach the highest content.
No amount of publicity and marketing is meaningful, only the Janoshik test report is the most convincing!
Industry-leading product quality, sold in 130 countries around the world
If you have any needs, please consult customer service
FAQ
Q1: How can you ensure the quality of your products?
A: All Cocer Pharmaceutical products have been strictly tested by Janoshik and come with all test reports. Product quality is at the top level in the industry.
Q2: What are the payment methods for purchasing your products?
A: You can pay by bank transfer, USDT, paypal, etc.
Q3: How long does it take for you to deliver the goods and for me to receive the goods.
A: Normally you can receive the goods on time within 7-12 days.
Q4: Can I get free samples?
A: Yes, you only need to pay the shipping fee to get our product samples.
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