Customization: | Available |
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CAS No.: | 24346-32-5 |
Formula: | off |
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Purity | 99%+ | Private customization | 2mg 5mg 10mg 15mg 20mg 30me etc. | |
Cleanliness | Sterile | Transportation time | 7-15days | |
Actual peptide content | Exceed the standard | Disguise | Can provide | |
Test Report | Janoshik Test Report | Resend policy | According to different countries | |
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TB5 is a synthetic version of the naturally occurring peptide present in virtually all human and animal cells, Thymosin Beta-4. This potent peptide is a member of a ubiquitous family of 16 related molecules with a high conservation of sequence and localization in most tissues and circulating cells in the body. TB5 not only binds to actin, but also blocks actin polymerization and is the actin-sequestering molecule in eukaryotic cells.
TB5 was identified as a gene that was up-regulated four-to-six fold during early blood vessel formation and found to promote the growth of new blood cells from the existing vessels. This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building and speeds up recovery time of muscles fibres and their cells. An additional key factor of TB5 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeleton. It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.
Studies demonstrate that TB5 is a potent, naturally occurring wound repair factor with anti-inflammatory properties. Tß4 is different from other repair factors, such as growth factors, in that it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight meaning it can travel relatively long distances through tissues. One of TB5 key mechanisms of action is its ability to regulate the cell-building protein, Actin, a vital component of cell structure and movement. Of the thousands of proteins present in cells, actin represents up to 10% of the total proteins which therefore plays a major role in the genetic makeup of the cell.
Peptides are composed of amino acids linked together by Peptides. The smallest Peptides can consist of three amino acids, such as thyrotropin-releasing hormone (TRH). Most Peptides can be made up of dozens or even hundreds of amino acids. The primary secretion organs for Peptides are the hypothalamus and the pituitary gland; however, Peptides have also been found in other organs, such as the gastrointestinal tract, brain tissue, lungs, and heart. Peptides are a type of endogenous substance that consists of protein chains containing polypeptide compounds. Examples of Peptides include thyrotropin-releasing hormone, Peptides and its analogs, Peptides and its analogs, adrenocorticotropic hormone, gonadotropins, Peptides and its analogs, Peptides-like Peptides, calcitonin, and parathyroid hormone.
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